Imatinib mesylate

Inquiry

For Research Use Only.

Size	Price	Stock	Quantity
10 g	$199	In stock

Category

Impurities

Cat.No.

NP3279

CAS

220127-57-1

Product Name

Imatinib mesylate

Structure

Product Details

Description

Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML).

Synonyms

CGP-57148B; CGP 57148B; CGP57148B; Gleevec, Imatinib

Molecular Weight

589.71

Molecular Formula

C29H31N7O.CH4SO3

Canonical SMILES

CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O

InChI

InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)

InChIKey

YLMAHDNUQAMNNX-UHFFFAOYSA-N

Melting Point

214-224°C

Purity

>98%

Appearance

White or off-white crystalline powder

Storage

2-8°C

Form

Oil