Hypaconitine

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For Research Use Only.

Size	Price	Stock	Quantity
20 mg	$285	In stock

Category

Alkaloids

Cat.No.

NP0562

CAS

6900-87-4

Product Name

Hypaconitine

Structure

Product Details

Description

Hypaconitine, a neuromuscular blocker, is a diterpene alkaloid found in the root of Aconitum carmichaelii. It is the primary constituent responsible for the neuromuscular blocking action of aconite root. It could inhibit CaM expression and Cx43 (Ser368) phosphorylation. It has anti-inflammatory effect.

Synonyms

(1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-acetatebenzoat; 15-tetraol,16,16-trimethoxy-4-(methoxymethyl)-20-methyl-18-aconitane-14; Aconitane-8,13,14,15-tetrol,1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-,8-acetate 14-benzoate, (1α,6α,14α,15α,16β)-; (1α,6α,14α,15α,16β)1,6,16-TriMethoxy-4-(MethoxyMethyl)-20-Methylaconitane-8,13,14,15-tetrol 8-Acetate 14-Benzoate; Japaconitine B1; Deoxymesaconitine;

Molecular Weight

615.3

Molecular Formula

C33H45NO10

Canonical SMILES

CC(=O)OC12C3C(CC(C3OC(=O)C4=CC=CC=C4)(C(C1O)OC)O)C56C(CCC7(C5C(C2C6N(C7)C)OC)COC)OC

InChI

1S/C33H45NO10/c1-17(35)44-33-21-19(14-31(38,28(42-6)26(33)36)27(21)43-29(37)18-10-8-7-9-11-18)32-20(40-4)12-13-30(16-39-3)15-34(2)25(32)22(33)23(41-5)24(30)32/h7-11,19-28,36,38H,12-16H2,1-6H3/t19-,20+,21-,22+,23+,24-,25?,26+,27-,28+,30+,31-,32+,33-/m1/s1

InChIKey

FIDOCHXHMJHKRW-VHQVDBNASA-N

Melting Point

172-175 °C

Purity

>98%

Solubility

Soluble in DMSO

Appearance

White powder

Application

A neuromuscular blocker could inhibit CaM expression and Cx43 (Ser368) phosphorylation. It has anti-inflammatory effect.

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

Store at -20 °C

Color

Yellow

Form

Powder

Packaging

20 mg

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