Description
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12-and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity. 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis. 2-(3,4-Dihydroxyphenyl)ethanol is a natural compound found in the herbs of Canarium album, it has antioxidant properties thus can be used in cosmetics material. It is not only used in the synthesis of cardiovascular drugs, but also as a safe and efficient antioxidant, used in beauty products and health products, with anti-aging, anti-wrinkle, free radical scavenger, whitening, and freckle removal effects.
Synonyms
DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol; 2-(3,4-Dihydroxyphenyl)ethanol; 4-(2-Hydroxyethyl)-1,2-benzenediol; 2-(3,4-Dihydroxyphenyl)ethyl Alcohol; Homoprotocatechuyl Alcohol; β-(3,4-Dihydroxyphenyl)ethanol; 3,4-DHPEA; 3,4-Dihydroxyphenylethanol
IUPAC Name
4-(2-hydroxyethyl)benzene-1,2-diol
Molecular Formula
C8H10O3
Canonical SMILES
C1=CC(=C(C=C1CCO)O)O
InChI
InChI=1S/C8H10O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,9-11H,3-4H2
InChIKey
JUUBCHWRXWPFFH-UHFFFAOYSA-N
Boiling Point
355.4±27.0°C (Predicted)
Density
1.321±0.06 g/cm3 (Predicted)
Solubility
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance
Clear, Faint Yellow to Yellow Liquid