Honokiol

Lignans

NP3936

35354-74-6

Honokiol

Honokiol is a polyphenol found in the genus Magnolia. Honokiol acts as an Akt inhibitor and also inhibits NF-κB, displaying anti-inflammatory, antiangiogenic and antitumor properties. It results in inhibition of bone metastatic growth of human prostate cancer cells. Honokiol has obvious antioxidant and anti-aging effects, thus can be used in cosmetic material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products.

Honokiol;35354-74-6;5,3'-Diallyl-2,4'-dihydroxybiphenyl;NSC 293100;3,5'-Diallyl-4,2'-dihydroxybiphenyl;3',5-Diallylbiphenyl-2,4'-diol;C18H18O2;3',5-diallyl-2,4'-biphenyldiol;CPD000387107;CHEMBL16901;2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol;CHEBI:5759;4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol;11513CCO0N;2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol;5,3'-Diallyl-biphenyl-2,4'-diol;MFCD00016674;NSC293100;[1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl-;3',5-Di-2-propen-1-yl[1,1'-biphenyl]-2,4'-diol;NSC-293100;Honokiol,(S);2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol;(1P)-3',5-di(prop-2-en-1-yl)[1,1'-biphenyl]-2,4'-diol;3',5-(5,5'-)Diallyl-[1,1'-biphenyl]-2,4'-(2,2'-)diol;SMR000387107;3',5-di(prop-2-en-1-yl)biphenyl-2,4'-diol;Purinol;(1,1'-BIPHENYL)-2,4'-DIOL, 3',5-DI-2-PROPENYL-;UNII-11513CCO0N;Honokiol?;-dihydroxydiphenyl;3',5-diallyl-[1,1'-biphenyl]-2,4'-diol;Honokiol, HO;3',5-Di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol; [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl- (9CI); 3',5-Diallyl-2,4'-biphenyldiol; Honokiol; NSC 293100;5,3′Honokiol - 95%;-Diallyl-2,4′FMLT BSASM H;HONOKIOL [MI];HONOKIOL [WHO-DD];Honokiol, analytical standard;cid_72303;MLS000759481;MLS001048916;MLS001423980;MLS006011755;SCHEMBL133034;REGID_for_CID_72303;GTPL11610;DTXSID30188845;3',1'-biphenyl)-2,4'-diol;HMS2051C12;HMS2271J07;HMS3393C12;HMS3656G03;(1,1'-BIPHENYL)-2,4'-DIOL, 3',5-DI-2-PROPEN-1-YL-;AMY40657;BCP28282;HY-N0003;AC-486;BBL027819;BDBM50157304;HB0328;s2310;STK801954;3'',5-diallylbiphenyl-2,4''-diol;Honokiol, >=98% (HPLC), powder;3,5'-diallyl-2',4-dihydroxybiphenyl;AKOS005622639;3',5-Diallyl-2,4'-dihydroxybiphenyl;CCG-100864;CS-1696;NC00114;5,3''-Diallyl-biphenyl-2,4''-diol;SMP2_000040;NCGC00163567-01;NCGC00163567-02;NCGC00163567-03;NCGC00163567-08;AS-15333;XH163752;5,3''''-Diallyl-biphenyl-2,4''''-diol;H1309;NS00011726;SW197494-3;EN300-7399522;A822747;SR-01000758208;Q-100425;Q5896650;SR-01000758208-5;{1,1'-Biphenyl]-2,4'-diol, 3,5-di-2-propenyl-;3'',5-di-2-propenyl-1,1''-biphenyl-2,4''-diol;BRD-K98493452-001-01-6;BRD-K98493452-001-14-9;Honokiol, European Pharmacopoeia (EP) Reference Standard;Z2065671480;[1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propen-1-yl;4-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-2-(prop-2-en-1-yl)phenol;InChI=1/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H;N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline; N-?(2-?Fluorophenyl)?-?5-?(6-?methyl-?2-?pyridinyl)?-?4-?[1,?2,?4]?triazolo[1,?5-?a]?pyridin-?6-?yl-1H-?imidazole-?2-?methanamine;Y4T;

2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol

541.6

C34H31N5O2

C[C@@H](C1=CC2=CC=CC=C2C=C1)NC(=O)C3=C4C(=CC=C3)N=C(N4CCCC(=O)NC)C5=CN=CC6=CC=CC=C65

InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

FVYXIJYOAGAUQK-UHFFFAOYSA-N

400.1°C at 760 mmHg

80-85°C

184°C

≥98%

1.107 g/cm3

Soluble in DMSO (36 mg/mL)

White Solid

anti-inflammatory and anti-cancer agent

Please store the product under the recommended conditions in the Certificate of Analysis.

White to Off-White

609-119-8

powder

Xi,N

9

29072990

9.89±0.48(Predicted)

1.601

UN 3077 9/PG 3

41-51/53

26-39-61

Stable at normal temperatures and pressures.

Honokiol has been used:to study its effects on plasmid hSirt3102-399 deacetylation activityas an antioxidant to study its cytoprotective role in human ovarian cancer cells (SKOV-3) and Chinese hamster ovary cells (CHOK1)to explore its effects on oxidative stress and mitochondrial dysfunction via a sirt3-dependent mannerfor intracerebroventricular (ICV) cannulation

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