Hederagenin

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For Research Use Only.

Category

Terpenes

Cat.No.

NP6265

CAS

465-99-6

Product Name

Hederagenin

Structure

Product Details

Description

Hederagenin is a triterpenoid saponin isolated from the herbs of Hedera nepalensis, it
exhibits the activity of antidepressant-like. Hederagenin can inhibit LPS-stimulated expression of iNOS, COX-2, and NF-κB.

Synonyms

(3-beta,4-alpha)-3,23-dihydroxyolean-12-en-28-oicacid;
Astrantiagenine;Hederagenicacid;Hederagenol;Caulosapogenin.

Molecular Weight

472.7

Molecular Formula

C30H48O4

InChIKey

PGOYMURMZNDHNS-MYPRUECHSA-N

Boiling Point

493.44°C (rough estimate)

Melting Point

332-334°

Purity

>97%

Density

0.9871 (rough estimate)

Solubility

methanol: soluble1mg/mL

Appearance

Powder

Application

anti-inflammatory

Storage

Sealed in dry,2-8°C

Alpha

D20 +81° (c = 0.7 in pyridine)

Chemical Properties

White Solid

Color

White to Off-White

Definition

ChEBI: A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer).

EINECS

207-369-9

Form

Solid

Hazard Class

HS Code

29181990

pKa

4.63±0.70(Predicted)

Refractive Index

1.4800 (estimate)

Risk Statements

Safety Statements

22-45-24/25

Uses

Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.

WGK Germany

λmax

405nm(H2SO4)(lit.)

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