Harman

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For Research Use Only.

Category

Alkaloids

Cat.No.

NP0843

CAS

486-84-0

Product Name

Harman

Structure

Product Details

Description

Harmane is an endogenous ligand for imidazoline binding sites. It binds to I1-sites in rat kidney (IC50 = 31 nM) and I2-sites (Ki = 49 nM). Harmane also acts as a potent inhibitor of monoamine oxidase A and B (IC50 = 0.5 and 5 μM, respectively).

Synonyms

Harman; Locuturin; NSC 54439; NSC-54439; NSC54439 Passiflorin; Aribine; Aribin; 1-Methyl-9H-pyrido[3,4-b]indole; Harman; Aribine; Locuturine

Molecular Weight

182.22

Molecular Formula

C12H10N2

Canonical SMILES

CC1=NC=CC2=C1NC3=CC=CC=C23

InChI

InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3

InChIKey

PSFDQSOCUJVVGF-UHFFFAOYSA-N

Purity

≥99% by HPLC

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