Harman

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0843
CAS
486-84-0
Product Name
Harman
Structure

Product Details

Description
Harmane is an endogenous ligand for imidazoline binding sites. It binds to I1-sites in rat kidney (IC50 = 31 nM) and I2-sites (Ki = 49 nM). Harmane also acts as a potent inhibitor of monoamine oxidase A and B (IC50 = 0.5 and 5 μM, respectively).
Synonyms
Harman; Locuturin; NSC 54439; NSC-54439; NSC54439 Passiflorin; Aribine; Aribin; 1-Methyl-9H-pyrido[3,4-b]indole; Harman; Aribine; Locuturine
Molecular Weight
182.22
Molecular Formula
C12H10N2
Canonical SMILES
CC1=NC=CC2=C1NC3=CC=CC=C23
InChI
InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3
InChIKey
PSFDQSOCUJVVGF-UHFFFAOYSA-N
Purity
≥99% by HPLC
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