Grossamide

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0387
CAS
80510-06-1
Product Name
Grossamide
Structure

Product Details

Description
Cis-Grossamide K is a natural alkaloid found in the herbs of Cannabis sativa L. Cis-Grossamide K exhibits a strong anti-melanogenic activity on the cells without high cell toxicity.
Synonyms
2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[3-[2-(4-hydroxyphenyl)et
hylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydrobenzofuran-3-carboxamide
IUPAC Name
(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[(E)-3-[2-(4-hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide
Molecular Weight
624.69
Molecular Formula
C36H36N2O8
Canonical SMILES
COC1=CC(=CC2=C1OC(C2C(=O)NCCC3=CC=C(C=C3)O)C4=CC(=C(C=C4)O)OC)C=CC(=O)NCCC5=CC=C(C=C5)O
InChI
InChI=1S/C36H36N2O8/c1-44-30-21-25(8-13-29(30)41)34-33(36(43)38-18-16-23-5-11-27(40)12-6-23)28-19-24(20-31(45-2)35(28)46-34)7-14-32(42)37-17-15-22-3-9-26(39)10-4-22/h3-14,19-21,33-34,39-41H,15-18H2,1-2H3,(H,37,42)(H,38,43)/b14-7+/t33-,34+/m1/s1
InChIKey
DROXVBRNXCRUHP-YRKLVFRVSA-N
Boiling Point
934.8±65.0°C (Predicted)
Purity
>97%
Density
1.315±0.06 g/cm3(Predicted)
Appearance
Powder
Application
anti-melanogenic
Form
Powder
pKa
9.78±0.35(Predicted)
Uses
Grossamide is an anti-inflammatory agent found in hemp seed. Grossamide is a potential therapeutic candidate for inhibiting neuroinflammation in neurodegenerative diseases.
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