Description
It is produced by the strain of Penicillum griseofulvum. It can inhibit the strains of ClassZygomycetes, Ascomycetes and Deuteromycetes (MIC is 1-20 μg/mL), It can also inhibit the crimping of the spore tube of garlic rot grape (MIC is 1 μg/mL). It has obvious inhibitory effect on metaphase mitosis of bone marrow, small intestine and Walker 256 cancer cells.
Synonyms
Curling factor; Fulvicin; Gris PEG; GrisPEG; Gris-PEG; Grisactin; Amudane; 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione; (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione
IUPAC Name
(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
Molecular Formula
C17H17ClO6
Canonical SMILES
CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
InChI
InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N
Boiling Point
469.04 °C (Predicted)
Density
1.2579 g/cm3 (Predicted)
Solubility
Slightly soluble in Chloroform, Ethyl Acetate, Acetone, Benzene, Dioxane
Appearance
ColoRed diamond or Acicular Crystal