Glycitin

Inquiry

For Research Use Only.

Category

Flavonoids

Cat.No.

NP1927

CAS

40246-10-4

Product Name

Glycitin

Structure

Product Details

Description

Glycitin is an isoflavonoid recently found in flowers of Pueraria thunbergianaI. It can be modified into the metabolite glycitein which has anti-inflammatory properties. It promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. It is effective in preventing bone loss and reversing the unfavorable changes of lipid metabolism. It may modulate differentiation of MSC to cause a lineage shift toward the osteoblast and away from the adipocytes, and could inhibit adipocytic transdifferen-tiation of osteoblasts. It could also be helpful in preventing the development of osteonecrosis.

Synonyms

7-(b-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; Glycitein-7-O-b-D-glucoside

IUPAC Name

3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Molecular Weight

446.40

Molecular Formula

C22H22O10

Canonical SMILES

COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)OC4C(C(C(C(O4)CO)O)O)O

InChI

InChI=1S/C22H22O10/c1-29-15-6-12-14(30-9-13(18(12)25)10-2-4-11(24)5-3-10)7-16(15)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1

InChIKey

OZBAVEKZGSOMOJ-MIUGBVLSSA-N

Boiling Point

751.1±60.0 °C at 760 mmHg

Melting Point

216-230 °C

Flash Point

264.1±26.4 °C

Purity

>98%

Density

1.5±0.1 g/cm3