Description
Glutathione (GSH) is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), and neutrophils in lung tissue, increase the level of serum Ca2+, and be useful for the treatment of ANP. Glutathione can be used not only as medicine but also as a base material for functional foods. It is widely used in functional foods for delaying aging, enhancing immunity, and anti-tumor. Glutathione is the main ingredient in ''whitening needle'' injections, and it is also the main ingredient in many beauty products on the market.
Synonyms
L-γ-Glutamyl-L-cysteinyl-glycine; Agifutol S; Bakezyme RX; Copren; Deltathione; GSH; Glutathion; Glutathione-SH; Glutide; Glutinal; Isethion; L-Glutathione; Neuthion; Reduced glutathione; Tathion; Tathione; Triptide; N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine
IUPAC Name
(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
Molecular Formula
C10H17N3O6S
Canonical SMILES
N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
InChI
InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChIKey
RWSXRVCMGQZWBV-WDSKDSINSA-N
Boiling Point
754.5±60.0°C (Predicted)
Solubility
Soluble in Aqueous Base (Slightly), DMSO (Slightly), Water (Slightly)
Appearance
White to Off-white Solid
Application
Ingredient of health care products.
Storage
Store at -20°C under inert atmosphere
Toxicity
ORL-MUS LD50 5000 mg/kg, IPR-MUS LD50 4020 mg/kg, SCU-MUS LD50 5000 mg/kg, IVN-RBT LD50 > 2000 mg/kg, IMS-MUS LD50 4000 mg/kg.