Description
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.
Synonyms
Gliclazide; Diamicron; Glimicron; Nordialex; Diaikron; S-1702; S-852; S1702; S852; S 1702; S 852
IUPAC Name
1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
Molecular Formula
C15H21N3O3S
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2
InChI
InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19)
InChIKey
BOVGTQGAOIONJV-UHFFFAOYSA-N
Solubility
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance
White crystalline powder
Application
Hypoglycemic Agents
Safety Statements
S25; S26; S36/37; S53
Stability
Stable at normal temperatures and pressures. Heat.