Ginsenoside Rh2

Inquiry

For Research Use Only.

Category

Triterpenoids

Cat.No.

NP7211

CAS

78214-33-2

Product Name

Ginsenoside Rh2

Structure

Product Details

Description

Ginsenoside Rh2 is extracted from the roots of Panax ginseng C. A. Mey. It has anticancer proliferation, differentiation and chemopreventive effects in certain cancer cell types. It suppresses the growth of A375-S2 cells in vitro by inducing apoptosis. It has the most potent inhibitory activity on β-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous anaphylaxis reaction. It can exhibit antiallergic activity originating from cell membrane-stabilizing and anti-inflammatory activity by the inhibition of NO and PGE2 production. Ginsenoside Rh2 can be used in health products.

Synonyms

20(S)-Ginsenoside-Rh2; 3-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol; Dammarane, β-D-glucopyranoside deriv.; (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside; 20(S)-Ginsenoside Rh2

IUPAC Name

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Molecular Weight

622.87

Molecular Formula

C36H62O8

Canonical SMILES

CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)O)C

InChI

InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1

InChIKey

CKUVNOCSBYYHIS-IRFFNABBSA-N

Boiling Point

726.4±60.0 °C | Condition: Press: 760 Torr

Melting Point

139-144 °C

Purity

98%

Density

1.19±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

Solubility

10 mM in DMSO

Appearance

White Solid

Application

Ingredient of health care products.

Shelf Life

2 month in rt, long time

Storage

-20°C Freezer

Form

Powder

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