Ginsenoside Rh1

Inquiry

For Research Use Only.

Category

Triterpenoids

Cat.No.

NP7218

CAS

63223-86-9

Product Name

Ginsenoside Rh1

Structure

Product Details

Description

Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits hypoallergenic and antiinflammatory properties. It acts as a weak phytoestrogen, presumably by binding and activating the estrogen receptor. It was also found to have a membrane-stabilizing action as revealed by differential scanning calorimetry. It can alleviate inflammatory symptoms in atopic dermatitis (AD) by reduction of IgE and IL-6 levels in peripheral blood, increase of Foxp3 expression in draining lymph nodes and suppression of inflammation in skin regions.

Synonyms

Sanchinoside Rh1; (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl-β-D-glucopyranoside; (20S)-6α-(β-D-Glucopyranosyloxy)-3β,12β,20-trihydroxydammara-24-ene; 3β,12β,20-Trihydroxy-5α-dammar-24-en-6α-yl β-D-glucopyranoside; 6α-(β-D-Glucopyranosyloxy)-dammara-24-ene-3β,12β,20-triol; Prosapogenin A2; Sanchinoside B2

IUPAC Name

(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Molecular Weight

638.89

Molecular Formula

C36H62O9

Canonical SMILES

CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C)O)C)O)C

InChI

1S/C36H62O9/c1-19(2)10-9-13-36(8,43)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(39)32(3,4)30(33)22(17-35(24,34)7)44-31-29(42)28(41)27(40)23(18-37)45-31/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31+,33+,34+,35+,36-/m0/

InChIKey

RAQNTCRNSXYLAH-RFCGZQMISA-N

Purity

>98%

Solubility

Soluble in DMSO

Appearance

White powder

Application

Exhibits anti-inflammatory effect.

Shelf Life

As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

Storage

Store at -20 °C

Form

Powder

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