Ginkgolide K

Inquiry
For Research Use Only.
Category
Diterpenoids
Cat.No.
NP1526
CAS
153355-70-5
Product Name
Ginkgolide K
Structure
Structure
Size Price Stock Quantity
5 mg $199 In stock

Product Details

Description
Ginkgolide K is extracted from the leaves of Ginkgo biloba L. It promotes angiogenesis after ischemia stroke and promotes astrocyte migration and proliferation after oxygen-glucose deprivation. It improves nerve injury after cerebral ischemia-reperfusion and inhibits PAF-induced platelet aggregation. It also can promote the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells and shows anti- Parkinson's disease activity. It shows neuroprotective effect and anti-oxidative stress on ischemic stroke.
Synonyms
9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)-2,3,10a,11-tetrahydro-4,11-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aS,10aR,11R,11aR)-
IUPAC Name
(1S,6R,7S,8S,10R,11R,12R,13R)-8-tert-butyl-6,12-dihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadec-16-ene-5,15,18-trione
Molecular Weight
406.38
Molecular Formula
C20H22O9
Canonical SMILES
CC1=C2C(C(C34C25C(=O)OC3CC(C46C(C(=O)OC6O5)O)C(C)(C)C)O)OC1=O
InChI
InChI=1S/C20H22O9/c1-6-9-10(27-13(6)23)11(21)19-8-5-7(17(2,3)4)18(19)12(22)14(24)28-16(18)29-20(9,19)15(25)26-8/h7-8,10-12,16,21-22H,5H2,1-4H3/t7-,8+,10+,11-,12-,16?,18-,19-,20+/m0/s1
InChIKey
MGXAKXRVQRODDX-NENMJSRPSA-N
Boiling Point
743.5±60.0°C (Predicted)
Purity
97.5%
Density
1.60±0.1 g/cm3 (Predicted)
Solubility
Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate
Appearance
Powder
Storage
Store at -20°C
Color
Yellow
Form
Powder
Packaging
5 mg
Products
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