Description
Ginkgolide C, extracted from the Ginkgo biloba leaves, a traditional Chinese medicine, significantly increases the formation of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), and studies showed that when platelets (108/ml
Synonyms
Ginkgolide C
15291-76-6
1,7-Dihydroxy-ginkgolide A
Ginkgolide C;
GINKGOKIDE C
AC1L4OUG
AC1Q6PCW
CTK8F0397
AR-1C0541
AR-1C0542
NSC335757
AN-8390
NSC-335757
TR-031689
N1908
L001208
I06-0420
(1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl
Molecular Formula
C20H24O11
Canonical SMILES
CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5O)C(C)(C)C)C(C(=O)OC6O4)O)O
InChI
1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3
InChIKey
AMOGMTLMADGEOQ-UHFFFAOYSA-N
Boiling Point
813.8±65.0 °C | Condition: Press: 760 Torr
Melting Point
>3000 °C(dec)
Solubility
Soluble in DMSO
Storage
Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -59°C for long term (months to years).
Alpha
D24 -14.7° (c = 1 in ethanol)
Chemical Properties
Crystalline Solid
pKa
10.88±0.70(Predicted)
Safety Statements
22-24/25
Uses
Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists