Ginkgolide B

For Research Use Only.
Category
Diterpenoids
Cat.No.
NP1517
CAS
15291-77-7
Product Name
Ginkgolide B
Structure

Product Details

Description
Ginkgolide B is a PAFR antagonist with IC50 of 3.6 μM.
Synonyms
Bilobalide B; Ginkgolide B; BN 52021; BN52021; BN-52021; BN 52051; BN52051; BN-52051
IUPAC Name
8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
Molecular Weight
424.4
Molecular Formula
C20H24O10
Canonical SMILES
CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O
InChI
InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3
InChIKey
SQOJOAFXDQDRGF-UHFFFAOYSA-N
Boiling Point
762.4±60.0 °C(Predicted)
Melting Point
280°C (dec.)
Purity
>98%
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 10 mg/ml).
Appearance
Powder
Application
Fibrinolytic Agents
Storage
Sealed in dry,Store in freezer, under -20°C
Alpha
D24 -52.6° (c = 1 in ethanol)
BRN
4727611
Chemical Properties
White Crystalline Solid
Color
Yellow
EINECS
604-876-0
F
10-21
Form
Powder
HS Code
29322090
Packaging
20 mg
pKa
pKa1 7.14; pKa2 8.60; pKa3 11.89(at 25 °C)
Safety Statements
24/25
Stability
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Uses
Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.
Water Solubility
Soluble in DMSO. Slightly soluble in water and ethanol
WGK Germany
3
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