Gimeracil

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3472

CAS

103766-25-2

Product Name

Gimeracil

Structure

Product Details

Description

Gimeracil is a pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines.

Synonyms

Gimeracil; chlorodihydroxypyridine.

IUPAC Name

5-chloro-4-hydroxy-1H-pyridin-2-one

Molecular Weight

145.54

Molecular Formula

C5H4ClNO2

Canonical SMILES

C1=C(C(=CNC1=O)Cl)O

InChI

InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)