Genistein

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For Research Use Only.

Size	Price	Stock	Quantity
5 g	$297	In stock

Category

Flavonoids

Cat.No.

NP1875

CAS

446-72-0

Product Name

Genistein

Structure

Product Details

Description

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation.

Synonyms

5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; Differenol A

IUPAC Name

5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one

Molecular Weight

270.24

Molecular Formula

C15H10O5

Canonical SMILES

C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

InChI

InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

InChIKey

TZBJGXHYKVUXJN-UHFFFAOYSA-N

Boiling Point

555.5±50.0°C at 760 mmHg

Melting Point

295-300°C

Flash Point

217.1°C

Purity

>98%

Density

1.5±0.1 g/cm3

Solubility

Soluble in DMSO (Slightly), Methanol (Slightly)

Appearance

Pale Yellow to Light Beige Solid

Application

antitumor agent

Storage

Store at -20°C under inert atmosphere

Form

Powder

Hazard Codes

HS Code

2932999099

MDL

MFCD00016952

Packaging

5 g

Refractive Index

1.732

Risk Statements

R36/38

RTECS

NR2392000

Safety Statements

S24/25

Vapor Pressure

6E-13mmHg at 25°C

WGK Germany

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