Description
Gelsevirine, isolated from the herbs of Gelsemium elegans, could be developed as the treatment of anxiety-related disorders in human patients. Their anxiolytic mechanism may be involved in the agonist action of glycine receptor in the brain.
Synonyms
Gelsemine, 1-methoxy-; 1-Methoxygelsemine
Molecular Formula
C21H24N2O3
Boiling Point
130-150°C (Press: 0.0001 Torr)
Density
1.34±0.1 g/cm3(Predicted)
Uses
Gelsevirine, is a derivative of gelsemine, the principle alkaloid of the yellow jasmine. Gelsemine activates spinal α3 glycine receptors which produces antinociception and gelsemine contains anxiolytic properties.