Description
Gartanin is isolated from the stem bark of Garcinia mangostana. It could be a multiple targeting agent into its chemopreventive properties for human urinary bladder cancer. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.
Synonyms
1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9H-xanthen-9-one
IUPAC Name
1,3,5,8-tetrahydroxy-2,4-bis(3-methylbut-2-enyl)xanthen-9-one
Molecular Formula
C23H24O6
Canonical SMILES
CC(=CCC1=C(C2=C(C(=C1O)CC=C(C)C)OC3=C(C=CC(=C3C2=O)O)O)O)C
InChI
1S/C23H24O6/c1-11(2)5-7-13-19(26)14(8-6-12(3)4)22-18(20(13)27)21(28)17-15(24)9-10-16(25)23(17)29-22/h5-6,9-10,24-27H,7-8H2,1-4H3
InChIKey
OJXQLGQIDIPMTE-UHFFFAOYSA-N
Boiling Point
644.4±55.0 °C(Predicted)
Density
1.326±0.06 g/cm3(Predicted)
Solubility
Soluble in chloroform.
Application
antifungal property; antioxidant, anti‑inflammatory properties; antineoplastic property
Definition
ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 5 and 8 and prenyl groups at positions 2 and 4.
Uses
1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one is an anti-proliferative compound. An isoprenylated xanthone which is an androgen receptor degradation enhancer. A potential neuroprotective agent.