Garcinone C

For Research Use Only.
Category
Xanthones
Cat.No.
NP7246
CAS
76996-27-5
Product Name
Garcinone C
Structure

Product Details

Description
Garcinone C is isolated from the fruits of Garcinia mangostana. It is the most potent inhibitor of AChE, and it exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines.
Synonyms
Garcinone-C; 9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-8-(3-hydroxy-3-Methylbutyl)-2-(3-Methyl-2-buten-1-yl)-
IUPAC Name
1,3,6,7-tetrahydroxy-8-(3-hydroxy-3-methylbutyl)-2-(3-methylbut-2-enyl)xanthen-9-one
Molecular Weight
414.45
Molecular Formula
C23H26O7
Canonical SMILES
CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)O)CCC(C)(C)O)O)C
InChI
InChI=1S/C23H26O7/c1-11(2)5-6-12-14(24)9-17-19(21(12)27)22(28)18-13(7-8-23(3,4)29)20(26)15(25)10-16(18)30-17/h5,9-10,24-27,29H,6-8H2,1-4H3
InChIKey
HLOCLVMUASBDDP-UHFFFAOYSA-N
Boiling Point
689.0±55.0 °C at 760 mmHg
Melting Point
216 - 218 °C
Purity
95%
Density
1.367 g/cm3
Appearance
Yellow powder
pKa
7.13±0.20(Predicted)
Uses
Garcinone C is isolated from the pericarps of Garcinia mangostana Linn which has multifunctional activities against Alzheimer's disease (AD).Acetylcholinesterase inhibitor.
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