Description
Ganoderol B also called ganodermadiol is a natural triterpenoid found in the fruiting body of Ganoderma lucidum, it is an angiotensin-converting enzyme inhibitor and is a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum. Ganoderol B exhibits the activity of anti-androgen.
Synonyms
(3beta,24E)-Lanosta-7,9(11),24-trien-3,26-diol;ganodermadiol;(24E)-5α-Lanosta-7,9(11),
24-triene-3β,26-diol
IUPAC Name
(3S,5R,10S,13R,14R,17R)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular Formula
C30H48O2
Canonical SMILES
CC(CCC=C(C)CO)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C
InChI
InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChIKey
AOXXVRDKZLRGTJ-AZIDVCJLSA-N
Application
anti-androgen