Description
Ganodermanontriol, a natural triterpene isolated from Ganoderma lucidum, it has the activities of anti-HIV-1, anti-oxidative and anti-complement, and also can induce anti-inflammatory activity in t-BHP-damaged hepatic cells through the expression of HO-1, and in which PI3K/Akt and p38 kinases are involved in vitro and in vivo
Synonyms
24,25,26-Trihydroxylanosta-7,9(11)-dien-3-one
IUPAC Name
(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S,6R)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
Molecular Formula
C30H48O4
Canonical SMILES
CC(CCC(C(C)(CO)O)O)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(=O)C4(C)C)C)C)C
InChI
InChI=1S/C30H48O4/c1-19(8-11-25(33)30(7,34)18-31)20-12-16-29(6)22-9-10-23-26(2,3)24(32)14-15-27(23,4)21(22)13-17-28(20,29)5/h9,13,19-20,23,25,31,33-34H,8,10-12,14-18H2,1-7H3/t19-,20-,23+,25+,27-,28-,29+,30-/m1/s1
InChIKey
KASALCUNLBTNAA-LIPCCPSCSA-N
Application
anti-HIV-1, anti-oxidative, anti-complement