Galantamine hydrobromide

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For Research Use Only.

Size	Price	Stock	Quantity
500 mg	$259	In stock
1 g	$470	In stock

Category

Alkaloids

Cat.No.

NP0561

CAS

1953-04-4

Product Name

Galantamine hydrobromide

Structure

Product Details

Description

Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells.

Synonyms

6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-; 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, monohydrobromide, (4aS,6R,8aS)-; Galanthamine, hydrobromide; (-)-Galantamine hydrobromide; (-)-Galanthamine hydrobromide; Galanthamine hydrogen bromide; Jilkon hydrobromide; Lycoremine hydrobromide; Nivalin; Nivaline; Nivaline (pharmaceutical); Razadyne; Reminyl; Tamilin

IUPAC Name

(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide

Molecular Weight

368.28

Molecular Formula

C17H21NO3.HBr

Canonical SMILES

CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br

InChI

InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChIKey

QORVDGQLPPAFRS-XPSHAMGMSA-N

Melting Point

255-256°C

Purity

≥95%

Solubility

Soluble in Methanol (Slightly, Sonicated), Water (Sparingly, Sonicated)

Appearance

White to Off-white Solid

Application

Nootropic Agents

Storage

Store at -20°C

Form

Powder

Packaging

500 mg / 1 g

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