Description
Friedelin isolated from the dry stem of Juncus effusus L. It may be beneficial to mimic insulin action, which would be useful in the treatment of diabetes type 2 patients.
Synonyms
FRIEDELAN-3-ONE; DA-FRIEDOOLEANAN-3-ONE;
IUPAC Name
(4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1H-picen-3-one
Molecular Formula
C30H50O
Canonical SMILES
CC1C(=O)CCC2C1(CCC3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C)C)C)C)C)C
InChI
InChI=1S/C30H50O/c1-20-21(31)9-10-22-27(20,5)12-11-23-28(22,6)16-18-30(8)24-19-25(2,3)13-14-26(24,4)15-17-29(23,30)7/h20,22-24H,9-19H2,1-8H3/t20-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1
InChIKey
OFMXGFHWLZPCFL-SVRPQWSVSA-N
Boiling Point
477.2±13.0 °C(Predicted)
Melting Point
262-265 °C (lit.)
Solubility
Chloroform (Slightly), methanol (Slightly)
Application
antibacterial; antimicrobial; antiulcer; anti-inflammatory; analgesic; antipyretic;
Alpha
D -27.8° (chloroform)
Uses
Friedelin is a flavonoid extract which displays radical scavenging and anti-typhoid activity.