Fluticasone propionate

For Research Use Only.
Category
Impurities
Cat.No.
NP3130
CAS
80474-14-2
Product Name
Fluticasone propionate
Structure

Product Details

Description
Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever).
Synonyms
Fluticasone Propionate, Cutivate, Flixonase, Flixotide, Flonase, Flovent; DSSTox_CID_25511; DSSTox_RID_80922; DSSTox_GSID_45511; NCGC00016943-01
IUPAC Name
[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular Weight
500.57
Molecular Formula
C25H31F3O5S
Canonical SMILES
CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF
InChI
InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16?,18+,19+,22+,23+,24+,25+/m1/s1
InChIKey
WMWTYOKRWGGJOA-ZHLGSTKJSA-N
Boiling Point
568.3±50.0 °C at 760 mmHg
Melting Point
272-273 °C
Flash Point
297.5±30.1 °C
Purity
>98%
Density
1.3±0.1 g/cm3
Solubility
Water: 0.51 mg/L
Appearance
White Solid
Application
the treatment of asthma and allergic rhinitis
Storage
Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
Form
Powder
Packaging
100 mg
Vapor Pressure
0.0±3.5 mmHg at 25°C
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