Flumethasone

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3153

CAS

2135-17-3

Product Name

Flumethasone

Structure

Product Details

Description

Flumethasone is a topical difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. A prompt decrease in inflammation, exudation and itching is experienced after application. It is commonly used in veterinary practice and has been used in cortiso assays to study early porcine conceptus development.

Synonyms

RS 2177; RS-2177; RS2177; NSC 54702; U-10,974; U-10974; Anaprime; Aniprime; Fluvet; Methagon; BRN 5645455; Cortexilar; Flucort

IUPAC Name

(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

Molecular Weight

410.45

Molecular Formula

C22H28F2O5

Canonical SMILES

CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C)F

InChI

InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

InChIKey

WXURHACBFYSXBI-GQKYHHCASA-N

Boiling Point

569.8°C at 760 mmHg

Melting Point

237-240°C

Flash Point

298.4°C

Purity

99%

Density

1.36 g/cm3

Appearance

White to Off-white Crystalline Powder

Application

Anti-Inflammatory Agents

Storage

Store at 2-8°C

Form

Powder

Hazard Codes

HS Code

2937229000

Refractive Index

1.579

Risk Statements

R40

RTECS

TU3832000

Safety Statements

S22-S36

Vapor Pressure

2.33E-15mmHg at 25°C

WGK Germany

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