Euscaphic acid

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For Research Use Only.

Size	Price	Stock	Quantity
5 mg	$519	In stock

Category

Terpenes

Cat.No.

NP6519

CAS

53155-25-2

Product Name

Euscaphic acid

Structure

Product Details

Description

Euscaphic acid is isolated from the dried fruit of Ziziphus jujuba. It inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.

Synonyms

Acuminatic acid

IUPAC Name

(1R,2R,4aS,6aR,6aS,6bR,8aR,10S,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

Molecular Weight

488.7

Molecular Formula

C30H48O5

Canonical SMILES

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O

InChI

InChI=1S/C30H48O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)/t17-,19-,20+,21-,22-,23-,26+,27-,28-,29-,30+/m1/s1

InChIKey

OXVUXGFZHDKYLS-QUFHAEKXSA-N

Boiling Point

602.7±55.0 °C at 760 mmHg

Melting Point

262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1))

Purity

98%

Density

1.19g/cm3

Solubility

methanol (Slightly), Pyridine (Slightly)

Appearance

Powder

Application

antifungal; anti-diabetic activity; anti-inflammatory

Storage

-20°C Freezer

Color

White to Off-White

EINECS

200-258-5

Form

Solid

pKa

4.47±0.70(Predicted)

Uses

Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.

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