Ethyl gallate

Phenols

NP5375

831-61-8

Ethyl gallate

Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB. Ethyl gallate inhibits hydrogen peroxide signaling, may represent an alternative class of vasopressors for use in septic shock. Ethyl gallate suppresses proliferation and invasion in human breast cancer cells by modulating the PI3K/Akt pathway, which may contribute to inhibiting their downstream targets such as NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9 in breast cancer cells, could be used as potential antioxidants with safe therapeutic application in cancer chemotherapy.

ethyl 3,4,5-trihydroxybenzoate

ethyl 3,4,5-trihydroxybenzoate

198.17

C9H10O5

CCOC(=O)C1=CC(=C(C(=C1)O)O)O

InChI=1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3

VFPFQHQNJCMNBZ-UHFFFAOYSA-N

447.3 °C at 760 mmHg

160 - 162 °C

> 98 %

1.424 g/cm³

Powder

anti-oxidant

Powder

MFCD00016430