Escin Ia

For Research Use Only.
Category
Triterpenoids
Cat.No.
NP7065
CAS
123748-68-5
Product Name
Escin Ia
Structure
Structure
Size Price Stock Quantity
10 mg $199 In stock

Product Details

Description
Escin Ia is a triterpenoid saponin isolated from A. chinensis. It was shown to inhibit HIV-1 protease with IC50 value of 35 μM.
Synonyms
Aescin A; alpha-Escin
IUPAC Name
(2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid
Molecular Weight
1131.3
Molecular Formula
C55H86O24
Canonical SMILES
CC=C(C)C(=O)OC1C(C2(C(CC1(C)C)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CO)OC(=O)C
InChI
InChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27+,28+,29+,30+,31+,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42-,43-,44-,47-,48-,49+,51-,52+,53+,54+,55-/m0/s1
InChIKey
AXNVHPCVMSNXNP-IVKVKCDBSA-N
Boiling Point
1140.6±65.0 °C at 760 mmHg
Flash Point
311.8±27.8 °C
Purity
>98%
Density
1.46
Solubility
In Vitro:
DMSO : 100 mg/mL(88.40 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.5 mg/mL (2.21 mM); Clear solution
Appearance
Powder
Storage
4°C, protect from light
* In solvent :
-80°C, 6 months
-20°C, 1 month (protect from light)
Form
Powder
Packaging
10 mg
Vapor Pressure
0.0±0.6 mmHg at 25°C
Online Inquiry
×
Top
0
Inquiry Basket

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x