Erlotinib

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For Research Use Only.

Size	Price	Stock	Quantity
10 g	$249	In stock

Category

Impurities

Cat.No.

NP3245

CAS

183321-74-6

Product Name

Erlotinib

Structure

Product Details

Description

Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy.

Synonyms

CP358774; CP 358774; CP-358774; NSC 718781; NSC718781; NSC-718781

IUPAC Name

N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine

Molecular Weight

393.44

Molecular Formula

C22H23N3O4

Canonical SMILES

COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC

InChI

InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)

InChIKey

AAKJLRGGTJKAMG-UHFFFAOYSA-N

Purity

>98%

Form

Powder

Packaging

10 g

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