Description
Epiyangambin is purified from the twigs of Hernandia ovigera. (+)-Epiyangambi is a phytotoxic lignan which shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. (+)-Epiyangambin has anti-platelet aggregation activity. Epiyangambin shows significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg/mL.
Synonyms
O,O-Dimethyllirioresinol A
IUPAC Name
(3R,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
Molecular Formula
C24H30O8
Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)OC)OC
InChI
InChI=1S/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21-,22+/m0/s1
InChIKey
HRLFUIXSXUASEX-WWLNLUSPSA-N