Description
Edgeworin is a DNA polymerase beta (pol beta) inhibitor that inhibits both the lyase and polymerase activities of DNA polymerase beta. Edgeworin can be isolated from Edgeworthia gardneri.
Synonyms
7-hydroxy-3,7''-dicoumaryl ether; 7-hydroxy-3-(2-oxochromen-7-yl)oxychromen-2-one
IUPAC Name
7-hydroxy-3-(2-oxochromen-7-yl)oxychromen-2-one
Molecular Formula
C18H10O6
Canonical SMILES
C1=CC(=CC2=C1C=CC(=O)O2)OC3=CC4=C(C=C(C=C4)O)OC3=O
InChI
InChI=1S/C18H10O6/c19-12-4-1-11-7-16(18(21)24-14(11)8-12)22-13-5-2-10-3-6-17(20)23-15(10)9-13/h1-9,19H
InChIKey
WNLKKLCKMRDNHF-UHFFFAOYSA-N