(-)-EBURNAMONINE

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0003
CAS
4880-88-0
Product Name
(-)-EBURNAMONINE
Structure

Product Details

Description
(-)-Eburnamonine is a vinca alkaloid shows protective effects on mice.
Synonyms
Vinburnine; CH846; CH-846; CH 846; Vincamone;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine Eburnamenin-14(15H)-one Derivative;
IUPAC Name
(15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one
Molecular Weight
294.39
Molecular Formula
C19H22N2O
Canonical SMILES
CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
InChI
1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
InChIKey
WYJAPUKIYAZSEM-MOPGFXCFSA-N
Boiling Point
441.9°C at 760 mmHg
Melting Point
168-170 °C
Purity
≥95%
Density
1.34 g/cm3
Solubility
Soluble in DMSO
Appearance
White powder
Application
Shows protective effects on mice from the lethal consequences of hypoxia.
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage
Store at -20 °C
Alpha
D25 -102° (chloroform) (Clauder); D -100° (c = 0.783 in chloroform) (Cartier)
Color
White
EINECS
225-490-5
F
8-10
Form
Powder
MDL
MFCD00064309
Merck
13,3520
pKa
8.13±0.40(Predicted)
Refractive Index
1.5600 (estimate)
RTECS
YY8575570
Safety Statements
22-24/25
Uses
Cerebral vasodilatator.
WGK Germany
2
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