Description
(-)-Eburnamonine is a vinca alkaloid shows protective effects on mice.
Synonyms
Vinburnine; CH846; CH-846; CH 846; Vincamone;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine Eburnamenin-14(15H)-one Derivative;
IUPAC Name
(15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one
Molecular Formula
C19H22N2O
Canonical SMILES
CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
InChI
1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
InChIKey
WYJAPUKIYAZSEM-MOPGFXCFSA-N
Boiling Point
441.9°C at 760 mmHg
Solubility
Soluble in DMSO
Application
Shows protective effects on mice from the lethal consequences of hypoxia.
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Alpha
D25 -102° (chloroform) (Clauder); D -100° (c = 0.783 in chloroform) (Cartier)
Refractive Index
1.5600 (estimate)
Safety Statements
22-24/25
Uses
Cerebral vasodilatator.