Domperidone

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3463

CAS

57808-66-9

Product Name

Domperidone

Structure

Product Details

Description

Domperidone is a medication developed by Janssen Pharmaceutica that acts as a peripherally-selective antagonist of the dopamine D2 and D3 receptors.

Synonyms

KW 5338; KW5338; KW-5338; Domperidone; Motilium; Domperidona

IUPAC Name

6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one

Molecular Weight

425.91

Molecular Formula

C22H24ClN5O2

Canonical SMILES

C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

InChI

InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

InChIKey

FGXWKSZFVQUSTL-UHFFFAOYSA-N

Melting Point

240-244°C

Purity

>98%

Solubility

50.4 [ug/mL] (The mean of the results at pH 7.4)

Appearance

White Solid

Application

Antiemetics

Products

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