Description
Lipoic acid is a very excellent natural antioxidant, with free radical scavenging effect, its ability to remove free radicals is more than 100 times that of vitamin C, especially suitable for anti-aging products. It has the effect of chelating metal ions, can bind to copper ions in tyrosinase, is a competitive inhibitor of tyrosinase, and has good whitening effect. However, lipoic acid has the problems of low solubility, poor stability and significant odor, which limits its application in cosmetics. The shortcomings of lipoic acid can be solved by supramolecular inclusion technology. It can be widely used in anti-aging, wrinkle removal, whitening, spot lightening, anti-inflammatory and anti-sensitivity, acne treatment, scar reduction, damage repair and other products, and it is compatible with lotion cream formula, gel formula and water formula.
Synonyms
Thioctic acid; alpha-Lipoic acid; (+-)-2-dithiolane-3-pentanoic acid; (+-)-2-dithiolane-3-valeric acid; (+/-)-2-dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid, (±)-; 1,2-Dithiolane-3-valeric acid, (±)-; (RS)-Lipoic acid; (RS)-α-Lipoic acid; (±)-Lipoic acid; (±)-Thioctic acid; (±)-α-Lipoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid; 5-(1,2-Dithiolan-3-yl)valeric acid; 6,8-Thioctic acid; 6-Thioctic acid; DL-6,8-Thioctic acid; DL-6-Thioctic acid; DL-Lipoic acid; DL-α-Lipoic acid; Alipure; Biletan; Byodinoral-R; dl-α-Lipoic acid; Espa-lipon; Liposan; Lipothion; NSC 628502; NSC 90788; Octolipen; Oktolipen; Protogen A; Pyruvate oxidation factor; Thioctic acid; Thioctsan; Tioctidasi; Tioctidasi acetate replacing factor; α-(±)-Lipoic acid; α-lipon 300; α-Liponic acid
IUPAC Name
5-(dithiolan-3-yl)pentanoic acid
Molecular Formula
C8H14O2S2
Canonical SMILES
C1CSSC1CCCCC(=O)O
InChI
InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
InChIKey
AGBQKNBQESQNJD-UHFFFAOYSA-N
Solubility
Soluble in Chloroform (Sparingly), DMSO (Slightly), Ethanol (50 mg/mL), Methanol (Slightly)
Appearance
Light-Yellow Solid
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Safety Statements
37/39-26-24/25-36
Stability
Stable. Incompatible with strong oxidizing agents.
Vapor Pressure
0.0±1.7 mmHg at 25°C