Diosbulbin B

For Research Use Only.
Category
Diterpenoids
Cat.No.
NP1748
CAS
20086-06-0
Product Name
Diosbulbin B
Structure

Product Details

Description
Diosbulbin B, a natural diterpenoid found in the roots of Dioscorea bulbifera, has hepatotoxicity, oral administration of DB for 12 consecutive days can lead to the oxidative stress liver injury in mice;ferulic acid prevents. Diosbulbin B exhibits the activity of anti-tumor and has inhibition of gastric cancer cell line SGC-7901 proliferation.
Synonyms
(2R,3aS,6S,6aS,7R,10R,11aR,11bS)-2-(3-Furanyl)octahydro-11b-methyl-4H-3a,6:7,10-di
methanofuro[2,3-c]oxepino[4,5-e]oxepin-4,8(6H)-dione
8,12:15,16-Diepoxy-19-nor-13(16),14-clerodadiene-17,6:18,2-diolide.
IUPAC Name
(1S,3R,5S,6R,8R,11R,12S,13S)-3-(furan-3-yl)-5-methyl-2,9,14-trioxapentacyclo[11.2.1.18,11.01,5.06,12]heptadecane-10,15-dione
Molecular Weight
344.4
Molecular Formula
C19H20O6
Canonical SMILES
CC12CC(OC13CC(C4C2CC5CC4C(=O)O5)OC3=O)C6=COC=C6
InChI
InChI=1S/C19H20O6/c1-18-6-13(9-2-3-22-8-9)25-19(18)7-14(24-17(19)21)15-11-4-10(5-12(15)18)23-16(11)20/h2-3,8,10-15H,4-7H2,1H3/t10-,11+,12+,13+,14-,15+,18-,19+/m0/s1
InChIKey
QEANLIISUSNNDX-YHPVUIEZSA-N
Boiling Point
574.8±50.0 °C(Predicted)
Melting Point
285 °C
Purity
>95%
Density
1.43 g/cm3
Appearance
Powder
Application
antitumor
Storage
2-8°C
Color
Yellow
Form
Powder
Packaging
10 mg
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