Dendrobine

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For Research Use Only.

Size	Price	Stock	Quantity
20 mg	$299	In stock

Category

Alkaloids

Cat.No.

NP0819

CAS

2115-91-5

Product Name

Dendrobine

Structure

Product Details

Description

Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord.

Synonyms

(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one; Dendroban-12-one; 12-Oxodendrobane; 7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-; Dendrobine Dendroban-12-one

IUPAC Name

(1S,4S,7S,8R,11R,12R,13S)-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one

Molecular Weight

263.38

Molecular Formula

C16H25NO2

Canonical SMILES

CC(C)C1C2C3CCC4C3(C(C1OC2=O)N(C4)C)C

InChI

InChI=1S/C16H25NO2/c1-8(2)11-12-10-6-5-9-7-17(4)14(16(9,10)3)13(11)19-15(12)18/h8-14H,5-7H2,1-4H3/t9-,10+,11+,12-,13-,14-,16+/m1/s1

InChIKey

RYAHJFGVOCZDEI-UFFNCVEVSA-N

Boiling Point

374.6±25.0 °C at 760 mmHg

Melting Point

135-136°C

Flash Point

132.8±14.0 °C

Purity

>98%

Density

1.101 g/cm3

Solubility

In Vitro:
DMSO : 33.33 mg/mL(126.55 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution
2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline)
Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution
3.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution

Appearance

Cryst.

Application

Analgesic/antipyretic

Storage

4°C, protect from light
* In solvent :
-80°C, 6 months
-20°C, 1 month (protect from light)

Form

Powder

Packaging

20 mg

Vapor Pressure

0.0±0.8 mmHg at 25°C

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