Dehydrotolvaptan

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3309

CAS

137973-76-3

Product Name

Dehydrotolvaptan

Structure

Product Details

Description

One of the impurities of Tolvaptan, which has been found to be a vasopressin V2 receptor antagonist and could probably be effective against hypertensive heart failure and could also be an effective renal protective agent.

Synonyms

5-Dehydro Tolvaptan; N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide; 7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-Oxo-2,3,4,5-tetrahydro-1H-1-benzazepine

IUPAC Name

N-[4-(7-chloro-5-oxo-3,4-dihydro-2H-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide

Molecular Weight

446.94

Molecular Formula

C26H23ClN2O3

Canonical SMILES

CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(=O)C4=C3C=CC(=C4)Cl)C

InChI

InChI=1S/C26H23ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15H,5,8,13H2,1-2H3,(H,28,31)

InChIKey

VENGMROMZOKURN-UHFFFAOYSA-N

Melting Point

>118 °C (dec.)

Purity

98.0%

Appearance

White Solid

Form

Powder

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