Dehydroleucodine

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For Research Use Only.

Category

Sesquiterpenoids

Cat.No.

NP5965

CAS

36150-07-9

Product Name

Dehydroleucodine

Structure

Product Details

Description

Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Study indicated that dehydroleucodine had cytotoxicity against human acute myeloid leukemia (AML) cell lines. It triggers senescence and apoptosis in association with accumulation of DNA damage markers.

Synonyms

Dehydroleucodin; (3aS,9aS,9bS)-6,9-dimethyl-3-methylidene-4,5,9a,9b-tetrahydro-3aH-azuleno[4,5-b]furan-2,7-dione

Molecular Weight

244.29

Molecular Formula

C15H16O3

Canonical SMILES

CC1=C2C(C3C(CC1)C(=C)C(=O)O3)C(=CC2=O)C

InChI

InChI=1S/C15H16O3/c1-7-4-5-10-9(3)15(17)18-14(10)13-8(2)6-11(16)12(7)13/h6,10,13-14H,3-5H2,1-2H3/t10-,13-,14-/m0/s1

InChIKey

SKNVIAFTENCNGB-BPNCWPANSA-N

Purity

97.5%

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