Dehydroleucodine

For Research Use Only.
Category
Sesquiterpenoids
Cat.No.
NP5965
CAS
36150-07-9
Product Name
Dehydroleucodine
Structure

Product Details

Description
Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Study indicated that dehydroleucodine had cytotoxicity against human acute myeloid leukemia (AML) cell lines. It triggers senescence and apoptosis in association with accumulation of DNA damage markers.
Synonyms
Dehydroleucodin; (3aS,9aS,9bS)-6,9-dimethyl-3-methylidene-4,5,9a,9b-tetrahydro-3aH-azuleno[4,5-b]furan-2,7-dione
Molecular Weight
244.29
Molecular Formula
C15H16O3
Canonical SMILES
CC1=C2C(C3C(CC1)C(=C)C(=O)O3)C(=CC2=O)C
InChI
InChI=1S/C15H16O3/c1-7-4-5-10-9(3)15(17)18-14(10)13-8(2)6-11(16)12(7)13/h6,10,13-14H,3-5H2,1-2H3/t10-,13-,14-/m0/s1
InChIKey
SKNVIAFTENCNGB-BPNCWPANSA-N
Purity
97.5%
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