Description
Dehydrojuncusol, a potent HCV inhibitor, targets HCV NS5A and is able to inhibit RNA replication of replicons harboring resistance mutations to anti-NS5A direct-acting antivirals. Dehydrojuncusol significantly inhibits HCV infection when added after virus inoculation of HCV genotype 2a (EC50=1.35 µM).
Synonyms
Dehydrojuncusol|117824-04-1|CHEMBL4060785|HY-N8188|CS-0140285
IUPAC Name
5-ethenyl-1,6-dimethylphenanthrene-2,7-diol
Molecular Formula
C18H16O2
Canonical SMILES
CC1=C(C=CC2=C1C=CC3=CC(=C(C(=C32)C=C)C)O)O
InChI
InChI=1S/C18H16O2/c1-4-13-10(2)17(20)9-12-5-6-14-11(3)16(19)8-7-15(14)18(12)13/h4-9,19-20H,1H2,2-3H3
InChIKey
IZVFYHBVHNNKGE-UHFFFAOYSA-N
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.