Description
Dehydrogeijerin is a coumarin that can be isolated from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi. Study shows that dehydrogeijerin reduces nitric oxide (NO) and inducible nitric oxide synthase (iNOS) production from LPS-stimulated Raw 264.7 cells, and decreases cyclooxigenase-2 (COX-2) and pro-inflammatory cytokine production. Dehydrogeijerin has the anti-inflammatory effects.
Synonyms
Pablohopin; 7-methoxy-6-(3-methylbut-2-enoyl)chromen-2-one
Molecular Formula
C15H14O4
Canonical SMILES
CC(=CC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)OC)C
InChI
InChI=1S/C15H14O4/c1-9(2)6-12(16)11-7-10-4-5-15(17)19-13(10)8-14(11)18-3/h4-8H,1-3H3
InChIKey
XJDSLGAFRQCARR-UHFFFAOYSA-N