De-O-methyllasiodiplodin

For Research Use Only.
Category
Phenols
Cat.No.
NP4707
CAS
32885-82-8
Product Name
De-O-methyllasiodiplodin
Structure

Product Details

Description
De-O-methyllasiodiplodin is a natural compound isolated from the rhizomes of Smilax glabra. De-O-methyllasiodiplodin exhibits radical scavenging and moderate antibacterial effects. It effectively lowers the blood glucose level in db/db mice possibly via ameliorating the expression of obesity-related pro-inflammatory cytokines, highlighting the potential of the marine natural product as a drug lead for the treatment of metabolic disorders. De-O-methyllasiodiplodin shows moderate suppression effects on induced NO production, suggesting that it has potential anti-inflammatory activity.
Synonyms
(9S)-13,15-dihydroxy-9-methyl-10-oxabicyclo[10.4.0]hexadeca-1(12),13,15-trien-11-one
IUPAC Name
(4S)-14,16-dihydroxy-4-methyl-3-oxabicyclo[10.4.0]hexadeca-1(12),13,15-trien-2-one
Molecular Weight
278.34
Molecular Formula
C16H22O4
Canonical SMILES
CC1CCCCCCCC2=CC(=CC(=C2C(=O)O1)O)O
InChI
InChI=1S/C16H22O4/c1-11-7-5-3-2-4-6-8-12-9-13(17)10-14(18)15(12)16(19)20-11/h9-11,17-18H,2-8H2,1H3/t11-/m0/s1
InChIKey
NFEVFCAOVZCHBN-NSHDSACASA-N
Melting Point
120-125 °C (hexane )
Appearance
Powder
Application
Mineralocorticoid Receptor Antagonists
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