DAURICINE

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0049
CAS
524-17-4
Product Name
DAURICINE
Structure

Product Details

Description
Dauricine had a good inhibition effect on tumor cells in urinary system. At the same time, Dauricine has certain inhibition effects on the primary cultured tumor cell.
Synonyms
4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenol; 4-[((1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]phenol; Dauricine; dauricine (8ci); Menispermum dauricum DC Extract; 6,6'-Di-O-Methyldauricoline
IUPAC Name
4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]phenoxy]phenol
Molecular Weight
624.77
Molecular Formula
C38H44N2O6
Canonical SMILES
CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC)OC
InChI
1S/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3
InChIKey
AQASRZOCERRGBL-UHFFFAOYSA-N
Boiling Point
712.3±60.0°C (Predicted)
Melting Point
115°C
Flash Point
384.6°C
Purity
>98%
Density
1.185±0.06 g/cm3(Predicted)
Solubility
DMSO (Slightly), Methanol (Slightly)
Appearance
Cryst.
Application
antiarrhythmic
Storage
-20°C Freezer, Under inert atmosphere
Alpha
D11 -139° in methanol
Color
light tan
Definition
ChEBI: A bisbenzylisoquinoline alkaloid resulting from the formal oxidative dimerisation of 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenol by attachment of the phenolic oxygen of one molecule to the benzene ring
f the second (ortho to the phenolic hydroxy group of the latter).
Form
Solid
MDL
MFCD26960929
Packaging
10 mg
pKa
9.31±0.45(Predicted)
Refractive Index
1.601
Uses
Dauricine is a bisbenzylisoquinoline allkaloid derivative that displays a noted number of pharmaceutical properties. It is known to induces severe lung toxicity in animals.
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