Damnacanthal

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For Research Use Only.

Size	Price	Stock	Quantity
5 mg	$1380	In stock

Category

Anthraquinones

Cat.No.

NP0889

CAS

477-84-9

Product Name

Damnacanthal

Structure

Product Details

Description

Damnacanthal is a natural compound isolated from the fruit of Morinda citrifolia Linn. Damnacanthal acts as a potent and selective inhibitor of p56lck tyrosine kinase. It inhibits p56lck autophosphorylation with IC50 of 17 nM.

Synonyms

1-Methoxy-2-formyl-3-hydroxy-9,10-anthraquinone; 3-Hydroxy-1-methoxyanthraquinone-2-aldehyde

IUPAC Name

3-hydroxy-1-methoxy-9,10-dioxoanthracene-2-carbaldehyde

Molecular Weight

282.25

Molecular Formula

C16H10O5

Canonical SMILES

COC1=C2C(=CC(=C1C=O)O)C(=O)C3=CC=CC=C3C2=O

InChI

InChI=1S/C16H10O5/c1-21-16-11(7-17)12(18)6-10-13(16)15(20)9-5-3-2-4-8(9)14(10)19/h2-7,18H,1H3

InChIKey

IPDMWUNUULAXLU-UHFFFAOYSA-N

Boiling Point

531.9±50.0°C (Predicted)

Melting Point

218-219°C

Purity

98%

Density

1.461±0.06 g/cm3(Predicted)

Solubility

Soluble in DMSO (up to 7 mg/mL)

Appearance

Yellow powder

Storage

-20°C

Color

Yellow

Form

Powder

pKa

5.26±0.20(Predicted)

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Uses

Damnacanthal-induced anti-inflammation is associated with inhibition of NF-κB activity. Damnacanthal is used in the treatment of inflammatory-related diseases.

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