D-Tetrahydropalmatine

Inquiry

For Research Use Only.

Category

Alkaloids

Cat.No.

NP0072

CAS

3520-14-7

Product Name

D-Tetrahydropalmatine

Structure

Product Details

Description

D-Tetrahydropalmatine, a natural alkaloid compound which is isolated from a traditional Chinese herb Rhizoma Corydalis (yanhusuo). D-Tetrahydropalmatine can not only inhibit dopamine and serotonin uptake of synaptosomes in the rat brain. but also show inh

Synonyms

(13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; 2,3,9,10-Tetramethoxy-13aβ-berbine; (+)-(R)-Tetrahydropalmatine; (+)-2,3,9,10-Tetramethoxyberbine

IUPAC Name

(13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline

Molecular Weight

355.41

Molecular Formula

C21H25NO4

Canonical SMILES

COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC

InChI

InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1

InChIKey

AEQDJSLRWYMAQI-QGZVFWFLSA-N

Boiling Point

482.9±45.0°C (Predicted)

Melting Point

138-139°C

Purity

>98%

Density

1.23g/cm3

Solubility

Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)

Appearance

Powder

Application

Adrenergic Agents

Storage

Refrigerator

Color

White to light beige

Form

Powder or Crystals

pKa

6.53±0.20(Predicted)

Uses

D-Tetrahydropalmatine also shows inhibitory effects on acetylcholinesterase and butyrylcholinesterase.

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