Description
Cycloastragenol, belongs to the triterpene saponins, is mainly obtained from the hydrolysis of Astragaloside IV. Cycloastradiol is the only telomerase activator found today. It delays the shortening of telomeres by increasing telomerase. Cycloastradiol is believed to have anti-aging effects. Cycloastragenol can be used in cosmetics material.
Synonyms
9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-, (3β,6α,16β,20R,24S)-; (3β,6α,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol; Astramembrangenin; Cyclosieversigenin; Cyclosiversigenin; Cyloastragenol; (2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyltetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthrene-4,7,9-triol
IUPAC Name
(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecane-6,9,14-triol
Molecular Formula
C30H50O5
Canonical SMILES
CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)O)O)C
InChI
InChI=1S/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21-,22-,23-,26+,27-,28+,29-,30+/m0/s1
InChIKey
WENNXORDXYGDTP-UOUCMYEWSA-N
Boiling Point
617.2±55.0°C at 760 mmHg
Solubility
Soluble in Methanol
Appearance
White to Almost White Powder to Crystal
Storage
Store in a cool and dry place and at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
pKa
14.57±0.29(Predicted)