Description
Cyclo(D-Leu-L-Pro) is a cyclodipeptide found in Phellinus igniarius. It exhibits antitumor and antifungal effects.
Synonyms
Cyclo(L-prolyl-D-leucyl); Cyclo(S-Pro-R-Leu); Cyclo-L-prolyl-D-leucine
IUPAC Name
(3R,8aS)-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Molecular Formula
C11H18N2O2
Canonical SMILES
CC(C)CC1C(=O)N2CCCC2C(=O)N1
InChI
InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9+/m1/s1
InChIKey
SZJNCZMRZAUNQT-BDAKNGLRSA-N
Boiling Point
427.6±34.0°C at 760 mmHg
Solubility
Soluble in Methanol, Ethyl Acetate
Uses
Cyclo(D-Leu-L-Pro) is used in the inhibitory effect of three diketopiperazines from marine-derived bacteria on secretory group IIa phospholipase a2.