Description
Cryptomoscatone D2 is isolated from the branch and the stem bark of Cryptocarya moschata. Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.
Synonyms
(2R)-2-[(E,2R,4R)-2,4-dihydroxy-6-phenylhex-5-enyl]-2,3-dihydropyran-6-one
IUPAC Name
2-(2,4-dihydroxy-6-phenylhex-5-enyl)-2,3-dihydropyran-6-one
Molecular Formula
C17H20O4
Canonical SMILES
C1C=CC(=O)OC1CC(CC(C=CC2=CC=CC=C2)O)O
InChI
InChI=1S/C17H20O4/c18-14(10-9-13-5-2-1-3-6-13)11-15(19)12-16-7-4-8-17(20)21-16/h1-6,8-10,14-16,18-19H,7,11-12H2/b10-9+/t14-,15+,16+/m0/s1
InChIKey
GOQOIZFMLWZVMB-GLBZDCTLSA-N