Cryptofolione

For Research Use Only.
Category
Phenols
Cat.No.
NP4695
CAS
160098-78-2
Product Name
Cryptofolione
Structure

Product Details

Description
Cryptofolione is purified from the fruits of Cryptocarya alba. Cryptofolione shows moderate cytotoxicity in both macrophages and T. cruzi amastigotes, and also displays a mild inhibitory effect on the promastigote form of Leishmania spp. Z-Cryptofolione and Cryptomoscatone D2 acts as highly efficacious inhibitors of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.
Synonyms
(2R)-2-[(1E,4S,6R,7E)-4,6-dihydroxy-8-phenylocta-1,7-dienyl]-2,3-dihydropyran-6-one
Molecular Weight
314.38
Molecular Formula
C19H22O4
Canonical SMILES
C1C=CC(=O)OC1C=CCC(CC(C=CC2=CC=CC=C2)O)O
InChI
InChI=1S/C19H22O4/c20-16(8-4-9-18-10-5-11-19(22)23-18)14-17(21)13-12-15-6-2-1-3-7-15/h1-7,9,11-13,16-18,20-21H,8,10,14H2/b9-4+,13-12+/t16-,17-,18-/m0/s1
InChIKey
JSKFCRSAYKODTM-RURAAYBUSA-N
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